History of treatment for headaches, migraines, a psychiatric condition, and diagnosis of ADHD have been shown to affect baseline ImPACT scores ( 9). Tests requiring baselines are particularly vulnerable to developmental influence, learning curves, practice effect ( 6) and volitional exaggeration ( 7, 8). Children with poorer academic achievement scores may do worse on these tests, particularly when reading is required ( 5). An individual test for TBI may not be effective in diagnosing a patient if the test has not been designed to assess the specific symptoms with which the patient is presenting ( 3).īecause of the heterogeneity of the normal spectrum of brain function, many concussion detection tests require baseline assessments ( 4). Current assessments for concussion, the most common type of TBI, rely on combining tests designed to evaluate functional domains known to be affected such as balance, memory, and cognition ( 2). Traumatic brain injury (often abbreviated as TBI) is a multifaceted disease that may result in any of over 21 symptoms ranging from dizziness to photophobia ( 1). Eye tracking has potential to serve as an objective “gold-standard” for detection of neurophysiologic disruption due to brain injury. non-concussion has a sensitivity and specificity that is useful as a baseline-free aid in diagnosis of concussion. The misclassification rate ( n = 282) was 31.6%.Ĭonclusion: A pre-specified algorithm and cutoff for diagnosis of concussion vs. Results: When concussion is defined by SCAT3 subsets, the sensitivity and specificity of an eye tracking algorithm was 80.4 and 66.1%, The AUC was 0.718. The sensitivity and specificity of eye tracking were calculated after plotting of the receiver operating characteristic curve and calculation of the AUC (area under curve). The results of an eye tracking-based classifier model were then validated against a pre-specified algorithm with a cutoff for concussed vs. Methods: Potentially concussed subjects recruited in emergency department and concussion clinic settings prospectively underwent eye tracking and a subset of the Sport Concussion Assessment Tool 3 at 6 sites. Introduction: In order to obtain FDA Marketing Authorization for aid in the diagnosis of concussion, an eye tracking study in an intended use population was conducted.
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